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Similarly, in breast cancer, LOH at this locus occurred in approximately 36% of breast cancer tissues, and GPx1 with a leucine-containing allele exhibited lower GPx1 activities in response to stimulation than GPx1 a proline-containing allele [88]

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Combination treatment with the Wnt/-catenin signaling pathway inhibitor DKK1 and the Frizzled-7 receptor-blocking agent Fz7-21 can significantly reduce -catenin and its downstream protein levels

This distinctive appearance helps confirm successful reconstitution

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